{"id":"CVE-2026-100845","title":"MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files","summary":"MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pick…","severity":"high","cvss":7.8,"cvssVector":"CVSS:3.1/AV:L/AC:L/PR:N/UI:R/S:U/C:H/I:H/A:H","cwe":["CWE-502"],"vendor":"project-monai","product":"monai","affected":["monai < 1.6.0"],"patched":["monai 1.6.0"],"published":"2026-09-27","updated":"2026-09-30","sourceUpdated":"2026-09-30T15:25:51.697","source":"NVD","sourceUrl":"https://nvd.nist.gov/vuln/detail/CVE-2026-100845","references":[{"url":"https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr","label":"disclosure@vulncheck.com"},{"url":"https://www.vulncheck.com/advisories/monai-before-1.6.0-remote-code-execution-via-numpyreader","label":"disclosure@vulncheck.com"},{"url":"https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-wg9g-w2j2-8pgr","label":"134c704f-9b21-4f2e-91b3-4a467353bcc0"},{"url":"https://github.com/Project-MONAI/MONAI/pull/8875"},{"url":"https://github.com/Project-MONAI/MONAI"},{"url":"https://github.com/Project-MONAI/MONAI/releases/tag/1.6.0"}],"tags":["nvd","cve.org","exploit-available","osv","pip"],"epss":0.00203,"epssPercentile":0.10154,"aliases":["GHSA-wg9g-w2j2-8pgr","PYSEC-2026-4020"],"ecosystem":"pip","exploitAvailable":true,"ssvc":{"exploitation":"poc","automatable":"no","technicalImpact":"total","timestamp":"2026-09-28T13:56:28.228012Z"},"ingestedAt":"2026-09-27T02:41:45.574Z","slug":"CVE-2026-100845","body":"## Overview\n\nMONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.\n\n## Affected\n\n- `monai < 1.6.0`\n\n## Remediation\n\nUpgrade past the affected range:\n\n- `monai 1.6.0`\n\n## Package advisory (CVE-2026-100845)\n\nAffected packages:\n\n- `monai < 1.6.0`\n\nPatched in:\n\n- `monai 1.6.0`\n\nSource: https://osv.dev/vulnerability/GHSA-wg9g-w2j2-8pgr","depth":"midnight","depthScore":55,"depthScoreParts":{"impact":42.9,"likelihood":0,"exploitation":12,"ransomware":0},"changes":[{"seq":211941,"id":"CVE-2026-100845","ts":1790604795641,"field":"exploit_available","old":"false","new":"true"}]}