{"id":"CVE-2026-100846","title":"MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py","summary":"MONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the dat…","severity":"high","cvss":7.6,"cvssVector":"CVSS:3.1/AV:N/AC:H/PR:H/UI:R/S:C/C:H/I:H/A:H","cwe":["CWE-502"],"vendor":"project-monai","product":"monai","affected":["monai < 1.5.2"],"patched":["monai 1.5.2"],"published":"2026-09-27","updated":"2026-10-08","sourceUpdated":"2026-10-08T16:17:00.040","source":"NVD","sourceUrl":"https://nvd.nist.gov/vuln/detail/CVE-2026-100846","references":[{"url":"https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4","label":"disclosure@vulncheck.com"},{"url":"https://www.vulncheck.com/advisories/monai-before-1.5.2-remote-code-execution-via-pickle-deserialization","label":"disclosure@vulncheck.com"},{"url":"https://github.com/Project-MONAI/MONAI/security/advisories/GHSA-89gg-p5r5-q6r4","label":"134c704f-9b21-4f2e-91b3-4a467353bcc0"},{"url":"https://github.com/Project-MONAI/MONAI/issues/8874#issuecomment-4752023161"},{"url":"https://github.com/Project-MONAI/MONAI/commit/9078a72f3992e49bd4560db510be9ec4ccf972cc"},{"url":"https://github.com/Project-MONAI/MONAI"},{"url":"https://github.com/Project-MONAI/MONAI/releases/tag/1.6.0"}],"tags":["nvd","cve.org","exploit-available","osv","pip"],"exploitAvailable":true,"ssvc":{"exploitation":"poc","automatable":"no","technicalImpact":"total","timestamp":"2026-09-30T15:52:35.963891Z"},"epss":0.00361,"epssPercentile":0.29714,"aliases":["GHSA-89gg-p5r5-q6r4","PYSEC-2026-4021"],"ecosystem":"pip","ingestedAt":"2026-09-27T02:41:45.575Z","slug":"CVE-2026-100846","body":"## Overview\n\nMONAI before 1.5.2 contains a deserialization of untrusted data vulnerability in the algo_from_pickle function in monai/auto3dseg/utils.py. The function reads a .pkl file and passes its contents to pickle.loads without validating the data source or content. If an application invokes algo_from_pickle on an attacker-supplied pickle file, an object defining __reduce__ is executed during deserialization, resulting in arbitrary code execution in the context of the application.\n\n## Affected\n\n- `monai < 1.5.2`\n\n## Remediation\n\nUpgrade past the affected range:\n\n- `monai 1.5.2`\n\n## Package advisory (CVE-2026-100846)\n\nAffected packages:\n\n- `monai < 1.6.0`\n\nPatched in:\n\n- `monai 1.6.0`\n\nSource: https://osv.dev/vulnerability/GHSA-89gg-p5r5-q6r4","depth":"midnight","depthScore":54,"depthScoreParts":{"impact":41.8,"likelihood":0.1,"exploitation":12,"ransomware":0},"changes":[{"seq":213736,"id":"CVE-2026-100846","ts":1790784724618,"field":"exploit_available","old":"false","new":"true"}]}